What is the CAS number for Cediranib?

The CAS number of Cediranib is 288383-20-0.

What is Cediranib (288383-20-0) used for?

Receptors for VEGF have central roles in vasculogenesis and angiogenesis and thus serve as targets for cancer therapy. Cediranib is a potent inhibitor of VEGF receptor tyrosine kinases, including VEGFR1, 2, and 3 (IC50s = 5, 1, and 3 nM, respectively). It also potently inhibits a variety of other receptor and non-receptor tyrosine kinases, including several in the platelet-derived growth factor, fibroblast growth factor, and endothelial growth factor receptor families. Cediranib blocks tubule formation by human umbilical vein endothelial cells in vitro and prevents angiogenesis as well as xenograft tumor growth in vivo. Because of these effects, cediranib has potential use in a range of cancers.InChI:InChI=1/C25H27FN4O3/c1-16-12-17-19(29-16)6-7-21(24(17)26)33-25-18-13-22(31-2)23(14-20(18)27-15-28-25)32-11-5-10-30-8-3-4-9-30/h6-7,12-15,29H,3-5,8-11H2,1-2H3

What is the CAS number for Cediranib?

The CAS number of Cediranib is 288383-20-0.

What is Cediranib (288383-20-0) used for?

Receptors for VEGF have central roles in vasculogenesis and angiogenesis and thus serve as targets for cancer therapy. Cediranib is a potent inhibitor of VEGF receptor tyrosine kinases, including VEGFR1, 2, and 3 (IC50s = 5, 1, and 3 nM, respectively). It also potently inhibits a variety of other receptor and non-receptor tyrosine kinases, including several in the platelet-derived growth factor, fibroblast growth factor, and endothelial growth factor receptor families. Cediranib blocks tubule formation by human umbilical vein endothelial cells in vitro and prevents angiogenesis as well as xenograft tumor growth in vivo. Because of these effects, cediranib has potential use in a range of cancers.InChI:InChI=1/C25H27FN4O3/c1-16-12-17-19(29-16)6-7-21(24(17)26)33-25-18-13-22(31-2)23(14-20(18)27-15-28-25)32-11-5-10-30-8-3-4-9-30/h6-7,12-15,29H,3-5,8-11H2,1-2H3

Chinese Manufacturer supply Cediranib 288383-20-0 in stock with high standard

Q: What is the Cediranib?

Cediranib is , while it's Molecular Formula is C 25 H 27 FN 4 O 3 . Cediranib is a drug for blocking angiogenesis, study on cervical cancer molecular targeted drug and clinical application progress, value of correlative biomakers in the understanding of tumor biology.

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Cediranib

Product Name Cediranib
cas 288383-20-0
purity 99%

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Chinese Manufacturer supply Cediranib 288383-20-0 in stock with high standard We supply high quality Cediranib (CAS 288383-20-0), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the Cediranib ?

Cediranib is , while it's Molecular Formula is C₂₅H₂₇FN₄O₃. Cediranib is a drug for blocking angiogenesis, study on cervical cancer molecular targeted drug and clinical application progress, value of correlative biomakers in the understanding of tumor biology.

How to get the best price on Cediranib?

Nantong Advance Chemical Co., Ltd is a quality supplier and manufacturer of Cediranib . You can buy high quality, low price Cediranib 288383-20-0 here. Contact us.