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Sumatriptan

  • Product Name Sumatriptan
  • cas 103628-46-2
  • purity 99%
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What is the Sumatriptan ?

Sumatriptan is White to crystalline powder, while it's Molecular Formula is C14H21N3O2S. Sumatriptan is a serotonin 5HT1-receptor agonist.

What is the CAS number for Sumatriptan ?

The CAS number of Sumatriptan is 103628-46-2.

More information of Sumatriptan 103628-46-2 are:

Synonyms

3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide;GR 43175;GR 43175X;Alsuma;BRN 6930870;Sumatriptanum;UNII-8R78F6L9VO;1H-Indole-5-methanesulfonamide, 3-(2-(dimethylamino)ethyl)-N-methyl-;1H-Indole-5-methanesulfonamide,3-[2-(dimethylamino)ethyl]-N-methyl-;

CAS?Number

103628-46-2

Molecular Formula

C14H21N3O2S

Molecular Weight

295.406

Density

1.243 g/cm3

Melting Point

169-171 °C

Boiling Point

497.7 °C at 760 mmHg

Flash Point

254.8 °C

HS CODE

2935904000

PSA

73.58000

LogP

2.79290

Pka

pKa 9.5 (Uncertain)

What is Sumatriptan (103628-46-2) used for?

Sumatriptan, also known as Imitrex, is a sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. It is a selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family) and was the first triptan approved in 1991 for the acute treatment of migraine headaches. Sumatriptan has the lowest oral bioavailability among all triptans due to its low lipophilicity.

InChI:InChI=1/C14H21N3O2S/c1-15-10-20(18,19)12-4-5-14-13(8-12)11(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3

Articles related to Sumatriptan:

Article

Source

Palladium-Catalyzed α-Arylation of Methyl Sulfonamides with Aryl Chlorides

Zheng, Bing,Li, Minyan,Gao, Gui,He, Yuying,Walsh, Patrick J.

supporting information, p. 2156 - 2162 (2016/07/16)

Unanticipated acyloxymethylation of sumatriptan indole nitrogen atom and its implications in prodrug design

Rodrigues, Tiago,Moreira, Rui,Guedes, Rita C.,Iley, Jim,Lopes, Francisca

experimental part, p. 344 - 350 (2009/04/04)

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