Top Quality Chinese Factory supply 2752-65-0 GAMBOGIC ACID

Q: What is the GAMBOGIC ACID?

GAMBOGIC ACID is , while it's Molecular Formula is C38H44O8. antiinflammatory, cytotoxic, inhibits HeLa cells in vitro;

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GAMBOGIC ACID

Product NameGAMBOGIC ACID
cas2752-65-0
purity99%

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Quality products?make an important contribution to long-term revenue and profitability. Top Quality Chinese Factory supply 2752-65-0 GAMBOGIC ACID

1.What is the GAMBOGIC ACID ?

antiinflammatory, cytotoxic, inhibits HeLa cells in vitro;

: gambogic acid pyridine salt

: 2752-65-0
(-)-gambogic acid

Conditions

Conditions	Yield
With hydrogenchloride; In diethyl ether; water; at 20 ℃; for 1h;	99%

: 25062-46-8,40979-16-6,34158-73-1
4-bromobenzaldehyde oxime

: 2752-65-0
(-)-gambogic acid

: C₄₅H₄₈BrNO₈

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 5h; Inert atmosphere;	80.7%

2.What is the CAS number for GAMBOGIC ACID ?

The CAS number of GAMBOGIC ACID is 2752-65-0.

More information of GAMBOGIC ACID 2752-65-0 are:

CAS?Number	2752-65-0
Density	1.296 g/cm³
Melting Point	88.5°C
Boiling Point	808.946 °C at 760 mmHg
Flash Point	251.446 °C
Vapor Pressure	1.21E-27mmHg at 25°C
Refractive Index	1.5290 (estimate)
HS CODE	29189900
PSA	119.36000
LogP	7.23930
Pka	4.58±0.36(Predicted)

3.What are another words for GAMBOGIC ACID ?

Synonyms?for?GAMBOGIC ACID 2752-65-0:b-Guttiferin;2-Butenoic acid,2-methyl-4-[(1R,3aS,5S,11R,14aS)-3a,4,5,7-tetrahydro-8-hydroxy-3,3,11-trimethyl-13-(3-methyl-2-butenyl)-11-(4-methyl-3-pentenyl)-7,15-dioxo-1,5-methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthen-1-yl]-,(2Z)- (9CI);2-Butenoic acid,2-methyl-4-[3a,4,5,7-tetrahydro-8-hydroxy-3,3,11-trimethyl-13-(3-methyl-2-butenyl)-11-(4-methyl-3-pentenyl)-7,15-dioxo-1,5-methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthen-1-yl]-,[1R-[1a,1(Z),3ab,5a,11b,14aS*]]-;Gambogic acid (7CI);R-Gambogic acid;1,5-Methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthene-1-crotonicacid, 3a,4,5,7-tetrahydro-8-hydroxy-a,3,3,11-tetramethyl-13-(3-methyl-2-butenyl)-11-(4-methyl-3-pentenyl)-7,15-dioxo-,(Z)- (8CI);

4.What is the molecular formula of GAMBOGIC ACID?

The chemical formula of ?GAMBOGIC ACID is?C38H44O8 which containing 38 Carbon atoms,44 Hydrogen atoms and 8 Oxygen atoms,and the molecular weight of??GAMBOGIC ACID?is 628.763.

5.What is GAMBOGIC ACID (2752-65-0) used for?

Gambogic acid (2752-65-0) induces apoptosis in a variety of cell lines acting as an antagonist of Bcl-2 family proteins (IC50 < 1 mM)1, however additional targets may contribute to its cytotoxicity. It suppresses cancer invasion and migration by inhibiting TGFb1-induced epithelial-to-mesenchymal transition.2 Potentiates the chemosensitivity of cancer cells to other agents.3 Down-regulates surviving, reversing docetaxel resistance in cancer cells.4

InChI:InChI=1/C38H44O8/c1-20(2)10-9-15-36(8)16-14-24-29(39)28-30(40)26-18-23-19-27-35(6,7)46-37(33(23)41,17-13-22(5)34(42)43)38(26,27)45-32(28)25(31(24)44-36)12-11-21(3)4/h10-11,13-14,16,18,23,27,39H,9,12,15,17,19H2,1-8H3,(H,42,43)/b22-13-/t23?,27?,36-,37?,38-/m1/s1

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